Description

(1S)-1-(3-Chloro-2-Fluorophenyl)Ethan-1-Ol CAS NO 1344948-04-4 is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. This compound matters as a key building block for the synthesis of complex, biologically active molecules, enabling the production of enantiomerically pure pharmaceuticals. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

This chiral alcohol intermediate is utilized in a variety of advanced synthetic pathways, including:

• Pharmaceutical Intermediate: A critical precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating chiral pesticides and herbicides with enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Used in the research and preparation of chiral ligands for asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high optical purity.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new synthetic routes in organic chemistry.

Basic Information

Item	Details
Product Name	(1S)-1-(3-Chloro-2-Fluorophenyl)Ethan-1-Ol
CAS No.	1344948-04-4
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	(S)-1-(3-Chloro-2-fluorophenyl)ethanol; (1S)-1-(3-Chloro-2-fluorophenyl)ethanol; (-)-1-(3-Chloro-2-fluorophenyl)ethanol; (S)-3-Chloro-2-fluoro-α-methylbenzyl alcohol; (S)-α-Methyl-3-chloro-2-fluorobenzyl alcohol; (1S)-1-(3-Chloro-2-fluorophenyl)ethan-1-ol; (S)-1-(3-Chloro-2-fluoro-phenyl)-ethanol
EINECS	Contact for details

Quality Control

Our (1S)-1-(3-Chloro-2-Fluorophenyl)Ethan-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and optical purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and optical rotation values are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.