Description

(1S)-1-Pyrimidin-2-Ylethanol is a chiral alcohol derivative of the pyrimidine heterocycle, serving as a valuable building block in advanced organic synthesis. Its enantiopure nature is critical for the development of pharmaceuticals and agrochemicals where stereochemistry dictates biological activity and efficacy. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for method development and the construction of complex molecular architectures.
• Fine Chemical Production: Integral to the manufacture of high-value, specialty chemicals requiring specific stereochemical configurations.

Basic Information

Product Name	(1S)-1-Pyrimidin-2-Ylethanol
CAS No.	1344914-38-0
Molecular Formula	C6H8N2O
Molecular Weight	124.14 g/mol
Synonyms	(S)-1-(Pyrimidin-2-yl)ethanol; (S)-α-Methyl-2-pyrimidinemethanol; (1S)-1-(2-Pyrimidinyl)ethanol; (S)-2-(1-Hydroxyethyl)pyrimidine; (S)-Pyrimidin-2-yl-ethanol; (S)-HPE; (S)-1-Pyrimidin-2-ylethanol; (S)-Enantiomer of 1-(2-Pyrimidyl)ethanol
EINECS	Contact for details

Quality Control

Our (1S)-1-Pyrimidin-2-Ylethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.