Description

(S)-1-(Isoquinolin-8-Yl)Ethanamine CAS NO 1344594-30-4 is a chiral amine derivative of isoquinoline, serving as a high-value building block in advanced organic synthesis. Its primary commercial value lies in its role as a key chiral intermediate for the research and development of novel pharmaceutical compounds, particularly in areas requiring specific stereochemistry. This product is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce a defined stereocenter into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential active pharmaceutical ingredients (APIs), especially in neurological and oncological research.
• Asymmetric Catalysis Ligand Precursor: Used in the development of novel chiral ligands for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for creating new chiral pesticides and herbicides with potentially improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances where the (S)-configuration is required.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new chemical methodologies and biological activities of isoquinoline derivatives.

Basic Information

Product Name	(S)-1-(Isoquinolin-8-Yl)Ethanamine
CAS No.	1344594-30-4
Molecular Formula	C11H12N2
Molecular Weight	172.23 g/mol
Synonyms	(S)-1-(8-Isoquinolyl)ethanamine; (S)-8-(1-Aminoethyl)isoquinoline; (S)-1-(Isoquinolin-8-yl)ethan-1-amine; (S)-α-Methyl-8-isoquinolinemethanamine; (S)-8-(1-Aminoethyl)isoquinoline; (S)-1-Aminoethyl-8-isoquinoline; (S)-1-(8-Quinolyl)ethylamine
EINECS	Contact for details

Quality Control

Every batch of (S)-1-(Isoquinolin-8-Yl)Ethanamine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity, meeting the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored in a cool, dry place, ideally under an inert atmosphere such as nitrogen or argon to maintain stability and purity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.