Description

(S)-1-(Isoquinolin-6-Yl)Ethanamine is a chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, which is critical for biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where stereoselectivity impacts efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Employed in methodological studies and the synthesis of complex natural product analogs.
• Fine Chemical Production: A building block for specialty chemicals requiring the isoquinoline scaffold with defined stereochemistry.

Basic Information

Product Name	(S)-1-(Isoquinolin-6-Yl)Ethanamine
CAS No.	1344588-21-1
Molecular Formula	C11H12N2
Molecular Weight	172.23 g/mol
Synonyms	(S)-1-(6-Isoquinolyl)ethanamine; (S)-6-(1-Aminoethyl)isoquinoline; (S)-α-Methyl-6-isoquinolinemethanamine; (S)-1-(Isoquinolin-6-yl)ethan-1-amine; (S)-6-(1-Aminoethyl)isoquinoline; (S)-1-(6-Isoquinolinyl)ethylamine; (S)-Amino(6-isoquinolyl)ethane
EINECS	Contact for details

Quality Control

Our production of (S)-1-(Isoquinolin-6-Yl)Ethanamine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chiral purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation. We implement controls aligned with ICH guidelines to support its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.