Description

5,6-Difluoro-2-(Hydroxymethyl)-Benzimidazole is a high-value fluorinated benzimidazole derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine atoms and a hydroxymethyl group, makes it a versatile intermediate for creating compounds with enhanced biological activity and specific electronic properties. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the research and development of new-generation fungicides and herbicides, where the fluorine atoms improve metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Ligand and Catalyst Development: The benzimidazole core acts as a chelating unit for constructing complex ligands used in catalytic systems.
• Fluorescent Probe Synthesis: Utilized in the design of fluorophores and molecular probes for biochemical sensing and imaging applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Item	Detail
Product Name	5,6-Difluoro-2-(Hydroxymethyl)-Benzimidazole
CAS No.	1344314-81-3
Molecular Formula	C8H6F2N2O
Molecular Weight	184.14 g/mol
Synonyms	2-(Hydroxymethyl)-5,6-difluorobenzimidazole; 5,6-Difluoro-1H-benzimidazole-2-methanol; 1H-Benzimidazole-2-methanol, 5,6-difluoro-; 5,6-Difluoro-2-(hydroxymethyl)-1H-benzo[d]imidazole; Difluorobenzimidazole methanol derivative
EINECS	Contact for details

Quality Control

Every batch of 5,6-Difluoro-2-(Hydroxymethyl)-Benzimidazole is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, is performed. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.