Description

5-Amino-2-Chloro-Thiazole-4-Carboxylic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiazole core enables the construction of complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its bioactive thiazole scaffold.
• Organic Synthesis Building Block: Employed in complex organic reactions, including cyclizations and cross-couplings, to construct diverse heterocyclic compounds.
• Material Science Research: Investigated as a monomer or precursor for functional polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	5-Amino-2-Chloro-Thiazole-4-Carboxylic Acid Ethyl Ester
CAS No.	1340583-40-5
Molecular Formula	C6H7ClN2O2S
Molecular Weight	206.65 g/mol
Synonyms	Ethyl 5-Amino-2-Chloro-1,3-Thiazole-4-Carboxylate; 2-Chloro-5-Aminothiazole-4-Carboxylic Acid Ethyl Ester; 4-Carbethoxy-5-Amino-2-Chlorothiazole; ACTE; 5-Amino-2-Chlorothiazole-4-Carboxylic Acid Ethyl Ester; Ethyl 2-Chloro-5-Aminothiazole-4-Carboxylate; 1340583-40-5
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Chloro-Thiazole-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. This material is moisture-sensitive (hygroscopic); ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.