Description

1-Iodo-3-Methanesulfonylpropane is a versatile bifunctional organic building block containing both an iodoalkyl and a mesyl (methanesulfonyl) group. This compound matters for its utility as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing molecular scaffolds, introducing functional handles, and facilitating cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for alkylation and nucleophilic substitution reactions.
• Cross-Coupling Reagent: Serves as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Heck, Negishi, Suzuki) to form carbon-carbon bonds.
• Ligand and Catalyst Synthesis: Used in the preparation of specialized ligands and organocatalysts where the mesyl and iodo groups allow for sequential functionalization.
• Polymer Modification: Acts as a functional monomer or grafting agent to introduce reactive sites into polymer backbones for creating advanced materials.
• Agrochemical Research: Employed in the synthesis of novel herbicide and pesticide candidates requiring specific halogenated alkyl chains.
• Chemical Biology Probes: Useful for labeling and bioconjugation strategies due to the reactivity of the iodo group with various nucleophiles.

Basic Information

Product Name	1-Iodo-3-Methanesulfonylpropane
CAS No.	1339388-73-6
Molecular Formula	C₄H₉IO₂S
Molecular Weight	248.08 g/mol
Synonyms	3-(Methanesulfonyl)-1-iodopropane; 1-Iodo-3-(methylsulfonyl)propane; 3-Iodopropyl methyl sulfone; Methanesulfonylpropyl iodide; MSI; Iodomesylpropane; Propane, 1-iodo-3-(methylsulfonyl)-; Iodo-mesyl propane
EINECS	Contact for details

Quality Control

Our 1-Iodo-3-Methanesulfonylpropane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.