Description

Carbamic Acid, n-[3-[3-(Aminosulfonyl)Phenyl]-1H-Indazol-5-Yl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of targeted small-molecule drugs, particularly in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of enzyme inhibitors.
• Oncology Drug Discovery: Used in the research and development of potential kinase inhibitors and other targeted cancer therapies.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and validate novel drug targets.
• Custom Synthesis Building Block: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.

Basic Information

Product Name	Carbamic Acid, n-[3-[3-(Aminosulfonyl)Phenyl]-1H-Indazol-5-Yl]-, 1,1-Dimethylethyl Ester
CAS No.	1338792-02-1
Molecular Formula	C20H22N4O4S
Molecular Weight	414.48 g/mol
Synonyms	tert-Butyl N-[3-[3-(aminosulfonyl)phenyl]-1H-indazol-5-yl]carbamate; 1,1-Dimethylethyl N-[3-[3-(aminosulfonyl)phenyl]-1H-indazol-5-yl]carbamate; 1338792-02-1; Carbamic acid, N-[3-[3-(aminosulfonyl)phenyl]-1H-indazol-5-yl]-, 1,1-dimethylethyl ester; tert-Butyl (3-(3-sulfamoylphenyl)-1H-indazol-5-yl)carbamate; BOC-protected sulfonamide indazole intermediate
EINECS	Contact for details

Quality Control

Every batch of Carbamic Acid, n-[3-[3-(Aminosulfonyl)Phenyl]-1H-Indazol-5-Yl]-, 1,1-Dimethylethyl Ester is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.