Description

4′-[[2,3-Dimethyl-5-[[[(1S)-1-(4-Nitrophenyl)Ethyl]Amino]Carbonyl]-1H-Indol-1-Yl]Methyl]- [1,1′-Biphenyl]-2-Carboxylic Acid is a high-purity, non-racemic chiral indole derivative designed for advanced research and development. This compound serves as a critical synthetic intermediate and a key scaffold in the discovery of novel bioactive molecules. It is primarily utilized by pharmaceutical, agrochemical, and biotechnology R&D teams focused on medicinal chemistry, structure-activity relationship (SAR) studies, and high-throughput screening.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in SAR studies to explore the biological activity of novel indole-based compounds.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function or protein interactions.
• Agrochemical Development: Investigated as a precursor for novel active ingredients in crop protection products.
• Academic & Institutional R&D: Employed in university and research institute laboratories for synthetic methodology development and bioactivity screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized, non-commercial compounds for client projects.

Basic Information

Product Name	4′-[[2,3-Dimethyl-5-[[[(1S)-1-(4-Nitrophenyl)Ethyl]Amino]Carbonyl]-1H-Indol-1-Yl]Methyl]- [1,1′-Biphenyl]-2-Carboxylic Acid
CAS No.	1338259-05-4
Molecular Formula	C33H29N3O5
Molecular Weight	547.60 g/mol
Synonyms	(S)-4'-(2,3-Dimethyl-5-((1-(4-nitrophenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid; 4'-[(2,3-Dimethyl-5-{[(1S)-1-(4-nitrophenyl)ethyl]carbamoyl}-1H-indol-1-yl)methyl][1,1'-biphenyl]-2-carboxylic Acid; Biphenyl-2-carboxylic acid, 4'-[[2,3-dimethyl-5-[[[(1S)-1-(4-nitrophenyl)ethyl]amino]carbonyl]-1H-indol-1-yl]methyl]-; 1338259-05-4; (S)-Enantiomer of the indole-biphenyl carboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and purity for sensitive R&D applications. Identity and purity are confirmed via advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and residual solvent levels is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.