Description

6-Bromo-8-Chloroisoquinolin-3-Ylamine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive isoquinoline core.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for catalysts, and advanced polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for target validation and mechanistic studies.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	6-Bromo-8-Chloroisoquinolin-3-Ylamine
CAS No.	1338254-58-2
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	3-Amino-6-bromo-8-chloroisoquinoline; 6-Bromo-8-chloro-3-isoquinolinamine; 6-Bromo-8-chloroisoquinolin-3-amine; 8-Chloro-6-bromoisoquinolin-3-amine; (6-Bromo-8-chloroisoquinolin-3-yl)amine; 1338254-58-2; 6-Bromo-8-chloro-3-aminoisoquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Chloroisoquinolin-3-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ISO standards ensure a reliable supply of this high-value intermediate for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.