Description

N1-Boc-4-Bromo-1H-Benzo[D][1,2,3]Triazole CAS NO 1338247-82-7 is a high-purity, protected heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those containing benzotriazole or brominated heterocycle motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific halogenated heterocyclic structures.
• Peptide Mimetics & PROTACs: The Boc-protected amine and reactive bromine site make it valuable for constructing peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs).
• Material Science: Employed in the synthesis of organic electronic materials, ligands for catalysts, and specialty polymers.
• Cross-Coupling Reactions: The bromine atom serves as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce diverse functional groups.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and bioactive compounds.

Basic Information

Product Name	N1-Boc-4-Bromo-1H-Benzo[D][1,2,3]Triazole
CAS No.	1338247-82-7
Molecular Formula	C₁₀H₁₀BrN₃O₂
Molecular Weight	284.11 g/mol
Synonyms	4-Bromo-1-[(tert-butoxy)carbonyl]-1H-benzotriazole; 1H-Benzotriazole, 4-bromo-1-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl 4-bromo-1H-benzo[d][1,2,3]triazole-1-carboxylate; 4-Bromo-1H-benzo[d][1,2,3]triazole-1-carboxylic acid tert-butyl ester; Boc-4-Bromo-benzotriazole; N-Boc-4-bromobenzotriazole; 4-Bromo-N-Boc-benzotriazole
EINECS	Contact for details

Quality Control

Our N1-Boc-4-Bromo-1H-Benzo[D][1,2,3]Triazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.