Description

5-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is a high-value, protected indazole derivative serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling the efficient construction of complex heterocyclic scaffolds, which are fundamental to pharmaceutical discovery and advanced material science. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-purity building blocks for drug discovery programs and the synthesis of novel functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and cellular processes.
• Material Science: A potential monomer or precursor for the synthesis of specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical reactions.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, complex organic molecules for client-specific applications.

Basic Information

Product Name	5-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole
CAS No.	1337882-14-0
Molecular Formula	C12H13IN2O
Molecular Weight	328.15 g/mol
Synonyms	5-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 1-(Oxan-2-yl)-5-iodo-1H-indazole; 5-Iodo-1-(THP)-1H-indazole; 5-Iodo-1-(tetrahydropyran-2-yl)-1H-indazole; 5-Iodo-1-(2-tetrahydropyranyl)-1H-indazole; 1H-Indazole, 5-iodo-1-(tetrahydro-2H-pyran-2-yl)-; 1337882-14-0
EINECS	Contact for details

Quality Control

Our 5-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to quality supports compliance with the standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.