Description

1-Aminoisoquinoline-6-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both an amino and a nitrile group on the isoquinoline scaffold, makes it a versatile precursor for constructing complex nitrogen-containing compounds. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including kinase inhibitors and other biologically relevant molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the creation of new pesticides and herbicides with specific modes of action.
• Material Science Research: Serves as a building block for organic electronic materials and advanced polymers.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies.

Basic Information

Product Name	1-Aminoisoquinoline-6-Carbonitrile
CAS No.	1337880-85-9
Molecular Formula	C10H7N3
Molecular Weight	169.18 g/mol
Synonyms	6-Cyano-1-aminoisoquinoline; 1-Isoquinolinamine, 6-cyano-; 1-Amino-6-cyanoisoquinoline; 6-Cyanoisoquinolin-1-amine; 1-Amino-6-isoquinolinecarbonitrile; AIQC; 1337880-85-9
EINECS	Contact for details

Quality Control

Our 1-Aminoisoquinoline-6-Carbonitrile is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support custom synthesis and can tailor purity grades to meet specific project requirements, from research to development scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.