Description

tert-Butyl 6-Hydroxy-1H-indazole-1-carboxylate is a high-purity, protected indazole derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, providing a versatile scaffold for the creation of novel pharmaceutical candidates. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of complex molecules targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and optimization of synthetic routes for clinical and commercial manufacturing.
• Bioconjugation & Probe Development: The protected hydroxyl and carboxylate groups allow for further functionalization, making it useful for creating biochemical probes and labeled compounds.
• Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	tert-Butyl 6-Hydroxy-1H-indazole-1-carboxylate
CAS No.	1337880-58-6
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	1H-Indazole-1-carboxylic acid, 6-hydroxy-, 1,1-dimethylethyl ester; 6-Hydroxy-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 6-hydroxyindazole-1-carboxylate; 1-BOC-6-hydroxy-1H-indazole; BOC-6-hydroxyindazole; 6-Hydroxyindazole-1-N-BOC; 1337880-58-6
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Hydroxy-1H-indazole-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.