Description

3-Chloro-6-Cyanoisoquinoline, also known as 3-Chloro-6-Cyano-2-Azanaphthalene, is a high-value, multi-functional heterocyclic building block with the CAS number 1337880-36-0. This compound is prized for its unique molecular scaffold, which serves as a critical intermediate in the synthesis of complex, biologically active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging its isoquinoline core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Chemical Synthesis: Utilized in academic and industrial R&D for constructing complex heterocyclic libraries via cross-coupling, cyclization, and functional group transformation reactions.
• Ligand & Catalyst Development: The nitrogen-containing heterocycle can act as a ligand for metal catalysts or be incorporated into organocatalysts.

Basic Information

Product Name	3-Chloro-6-Cyanoisoquinoline, 3-Chloro-6-Cyano-2-Azanaphthalene
CAS No.	1337880-36-0
Molecular Formula	C10H5ClN2
Molecular Weight	188.61 g/mol
Synonyms	3-Chloro-6-cyanoisoquinoline; 3-Chloro-6-cyano-2-azanaphthalene; 6-Cyano-3-chloroisoquinoline; Isoquinoline, 3-chloro-6-cyano-; 1337880-36-0; 3-Chloro-6-cyano-1-azanaphthalene; 3-Chloro-6-cyano-2-azanaphthalene; 3-Chloro-6-cyanoisoquinoline (principal name)
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-6-Cyanoisoquinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be stored away from light. Keep away from incompatible materials such as strong alkalis and fluorides.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.