Description

3-Chloro-2-Azanaphthalene-7-Carboxaldehyde, also known as 3-Chloro-7-formylisoquinoline, is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both a reactive aldehyde group and a halogenated nitrogen-containing ring system, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Acts as a starting material for creating sophisticated chelating ligands used in catalysis and material science.
• Fluorescent Probe Development: The formyl group allows for derivatization to create dyes and molecular probes for biochemical sensing and imaging.
• Material Science Precursor: Utilized in the synthesis of organic semiconductors and conductive polymers due to its planar, conjugated structure.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	3-Chloro-2-Azanaphthalene-7-Carboxaldehyde / 3-Chloro-7-Formylisoquinoline
CAS No.	1337879-96-5
Molecular Formula	C10H6ClNO
Molecular Weight	191.61 g/mol
Synonyms	3-Chloro-7-formylisoquinoline; 3-Chloro-7-isoquinolinecarboxaldehyde; 3-Chloro-2-azanaphthalene-7-carbaldehyde; 3-Chloro-7-aldehyde-isoquinoline; 3-Chloro-7-carboxaldehyde-isoquinoline; 3-Chloro-7-isoquinolinecarbaldehyde; 3-Chloro-7-formyl-2-azanaphthalene; 3-Chloro-7-formyl-isoquinoline
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-7-formylisoquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as identity, purity (HPLC), and impurity profile. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.