Description

n-(5-Bromo-2,3-dihydrothiophen-2-yl)acetamide is a specialized brominated heterocyclic acetamide derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scaffold diversification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the thiophene and bromine motifs for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular tag in probe development.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	n-(5-Bromo-2,3-dihydrothiophen-2-yl)acetamide
CAS No.	1337879-57-8
Molecular Formula	C6H8BrNOS
Molecular Weight	220.10 g/mol
Synonyms	Acetamide, N-(5-bromo-2,3-dihydro-2-thienyl)-; 5-Bromo-2,3-dihydrothiophene-2-acetamide; 2-Acetamido-5-bromo-2,3-dihydrothiophene; N-(5-Bromo-2,3-dihydrothien-2-yl)acetamide; 1337879-57-8; 5-Bromo-2-acetamido-2,3-dihydrothiophene
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-2,3-dihydrothiophen-2-yl)acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.