Description

L-Alanine, n-[(R)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl]-, 1-Methylethyl Ester is a specialized organophosphorus compound derived from the amino acid L-alanine, featuring a pentafluorophenoxy substituent. This molecule is of significant interest as a high-value chemical intermediate or building block in advanced synthetic chemistry, particularly for the development of novel active ingredients. It is primarily utilized by research institutions and industrial R&D teams focused on pharmaceuticals, agrochemicals, and materials science, where its unique structure enables the creation of compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and synthesis of new drug candidates, especially those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the phosphinyl and pentafluorophenoxy groups can contribute to biological activity.
• Chemical Biology & Proteomics: Acts as a precursor for activity-based probes or affinity labels to study enzyme function and mechanisms.
• Peptidomimetics & Bioactive Molecule Synthesis: Incorporated into peptide analogs to enhance stability, bioavailability, or receptor binding affinity.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique surface or degradation properties.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial production of complex organic molecules.

Basic Information

Product Name	L-Alanine, n-[(R)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl]-, 1-Methylethyl Ester
CAS No.	1337529-56-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Isopropyl (R)-N-[(2,3,4,5,6-pentafluorophenoxy)(phenoxy)phosphoryl]-L-alaninate; (R)-Isopropyl 2-(((2,3,4,5,6-pentafluorophenoxy)(phenoxy)phosphoryl)amino)propanoate; L-Alanine, N-[(R)-(pentafluorophenoxy)phenoxyphosphinyl]-, isopropyl ester; Pentafluorophenyl phenyl L-alaninylphosphonate isopropyl ester; Alanine phosphonate derivative; Fluorinated phosphonate ester; Research chemical 1337529-56-2
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical research and development projects. Our quality systems are designed to support cGMP and ISO standards where required, guaranteeing reliable material for scale-up and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Optical Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.