Description

7-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is a high-value, synthetically versatile heterocyclic building block. This compound is critical for medicinal chemistry research and development, serving as a key precursor in the synthesis of complex pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly within the central nervous system and oncology domains.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• API Development: Used in the research and process development of Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Chemical Biology Probe Synthesis: Employed to create specialized molecules for studying biological mechanisms and target validation.
• Ligand and Scaffold Development: Serves as a core structure for designing and optimizing ligands in drug discovery.
• Academic and Contract Research: Essential for synthetic organic chemistry research in academic institutions and CROs (Contract Research Organizations).
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	7-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
CAS No.	1336939-62-8
Molecular Formula	C₁₀H₁₀BrNO₂
Molecular Weight	256.10 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 3-Isoquinolinecarboxylic acid, 7-bromo-1,2,3,4-tetrahydro-; 7-Bromo-THIQ-3-COOH; 7-Br-THIQ-3-CA; 7-Bromo-3-carboxy-1,2,3,4-tetrahydroisoquinoline; 7-Bromo-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.