Description

Ethyl 4-Amino-2-(4-Methylpiperazin-1-Yl)-1,3-Thiazole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique thiazole-piperazine hybrid structure. This compound is critical for medicinal chemistry research and development, serving as a key building block for synthesizing novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring targeted molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Employed in the creation of molecular probes to study biological pathways and protein interactions due to its specific heterocyclic architecture.
• Fine Chemical Synthesis: Serves as a specialized building block for the multi-step synthesis of complex, high-value organic molecules in contract research and manufacturing (CRAM) organizations.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl 4-Amino-2-(4-Methylpiperazin-1-Yl)-1,3-Thiazole-5-Carboxylate
CAS No.	1334498-23-5
Molecular Formula	C11H17N5O2S
Molecular Weight	283.35 g/mol
Synonyms	Ethyl 4-amino-2-(4-methyl-1-piperazinyl)-1,3-thiazole-5-carboxylate; 4-Amino-2-(4-methylpiperazin-1-yl)thiazole-5-carboxylic acid ethyl ester; 2-(4-Methylpiperazin-1-yl)-4-amino-1,3-thiazole-5-carboxylic acid ethyl ester; 1334498-23-5; 5-Thiazolecarboxylic acid, 4-amino-2-(4-methyl-1-piperazinyl)-, ethyl ester; CAS 1334498-23-5
EINECS	Contact for details

Quality Control

Our Ethyl 4-Amino-2-(4-Methylpiperazin-1-Yl)-1,3-Thiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.