Description

P,p-Bis(4-(Trifluoromethyl)Phenyl)Phosphinic Amide is a high-value, specialized organophosphorus compound characterized by its unique trifluoromethylphenyl substituents. This structure makes it a critical intermediate and ligand in advanced chemical synthesis, particularly valued for its electronic and steric properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in catalysis, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Catalyst Ligand: Used as a sophisticated ligand in transition metal catalysis for cross-coupling reactions, enabling the formation of complex carbon-carbon and carbon-heteroatom bonds.
• Agrochemical Research: Employed in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Acts as a monomer or additive in the synthesis of advanced polymers, coatings, and flame-retardant materials with specific thermal and chemical resistance properties.
• Organic Electronics: Investigated for use in the development of organic light-emitting diodes (OLEDs) and semiconductors due to its electron-withdrawing characteristics.
• Chemical Research & Development: A versatile tool for academic and industrial R&D in exploring new reaction methodologies and creating functionalized molecules.

Basic Information

Item	Details
Product Name	P,p-Bis(4-(Trifluoromethyl)Phenyl)Phosphinic Amide
CAS No.	1333316-91-8
Molecular Formula	C14H10F6NOP
Molecular Weight	353.20 g/mol
Synonyms	Bis[4-(trifluoromethyl)phenyl]phosphinic amide; P,P-Bis(4-trifluoromethylphenyl)phosphinic amide; N,N-Bis[4-(trifluoromethyl)phenyl]phosphinamide; Phosphinic amide, P,P-bis[4-(trifluoromethyl)phenyl]-; (4-(Trifluoromethyl)phenyl)phosphinic amide dimer; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of P,p-Bis(4-(Trifluoromethyl)Phenyl)Phosphinic Amide is produced and tested under strict quality management protocols to ensure consistency and purity for demanding R&D and scale-up applications. Our standard quality assurance includes identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment. We support cGMP-compliant production for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.