Description

6-Chloro-4-(Trifluoromethyl)Indoline-2,3-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and trifluoromethylated indole-dione structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily sought after by research institutions, agrochemical developers, and pharmaceutical manufacturers engaged in the development of new drugs and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Synthesis: Employed in organic chemistry research as a versatile scaffold for constructing heterocyclic compounds and fluorinated analogs.
• Bioconjugation & Probe Development: Utilized in biochemical research for developing fluorescent probes or affinity labels due to its reactive carbonyl groups.

Basic Information

Product Name	6-Chloro-4-(Trifluoromethyl)Indoline-2,3-Dione
CAS No.	1332605-88-5
Molecular Formula	C9H3ClF3NO2
Molecular Weight	249.57 g/mol
Synonyms	6-Chloro-4-(trifluoromethyl)isatin; 6-Chloro-4-trifluoromethyl-2,3-dioxoindoline; 4-(Trifluoromethyl)-6-chloroisatin; 6-Chloro-4-(trifluoromethyl)-1H-indole-2,3-dione; 2,3-Dihydro-6-chloro-4-(trifluoromethyl)-2,3-dioxo-1H-indole; 6-Chloro-4-trifluoromethylindoline-2,3-dione
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-(Trifluoromethyl)Indoline-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.