Description

6-Chloro-1-Tosyl-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrrolopyridine core. This compound is of significant commercial importance as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted drug candidates, especially those acting on protein kinases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and selectivity.
• Biochemical Tool Compound: Serves as a core scaffold for creating probes and inhibitors used in biochemical and cellular assays to study disease pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	6-Chloro-1-Tosyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1332605-39-6
Molecular Formula	C16H12ClN2O2S
Molecular Weight	331.80 g/mol
Synonyms	6-Chloro-1-(4-methylphenyl)sulfonyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-chloro-1-[(4-methylphenyl)sulfonyl]-; 6-Chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1-p-toluenesulfonyl-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1-(p-tolylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1332605-39-6
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-Tosyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.