Description

5-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate the imidazopyridine scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas, including central nervous system (CNS) disorders and infectious diseases.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and develop novel drug candidates.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study biological pathways and protein functions.
• Agrochemical Synthesis: Employed as a precursor in the development of new pesticides and herbicides, leveraging its heterocyclic bioactivity.
• Material Science Research: Investigated as a potential monomer or precursor for functional organic materials, such as organic semiconductors or ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide
CAS No.	1332589-39-5
Molecular Formula	C₁₀H₁₀BrN₂O₂·HBr
Molecular Weight	350.02 g/mol
Synonyms	Ethyl 5-Bromoimidazo[1,2-a]pyridine-2-carboxylate Hydrobromide; 5-Bromoimidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester HBr Salt; 5-Bromo-2-(ethoxycarbonyl)imidazo[1,2-a]pyridin-1-ium Bromide; 5-Bromoimidazo[1,2-a]pyridine-2-carboxylate ethyl ester hydrobromide; 1332589-39-5; 5-Br-Imidazo[1,2-a]Pyridine-2-CAEE HBr
EINECS	Contact for details

Quality Control

Our 5-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.