Description

n-(1,3-Thiazol-5-Ylmethyl)Cyclopropanaminedihydrochloride is a high-purity, advanced pharmaceutical intermediate with a specific molecular architecture. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drug candidates, leveraging its unique cyclopropane and thiazole functionalities.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug molecules, especially for central nervous system (CNS) and anti-infective therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to enhance drug potency and selectivity.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Bioconjugation & Probe Development: Utilized in creating chemical probes and bioconjugates for biochemical assays and diagnostic research due to its reactive amine group.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of investigational new drugs (INDs).

Basic Information

Product Name	n-(1,3-Thiazol-5-Ylmethyl)Cyclopropanaminedihydrochloride
CAS No.	1332531-54-0
Molecular Formula	C8H13N2S • 2HCl
Molecular Weight	249.18 g/mol (Free base: 169.26 g/mol)
Synonyms	Cyclopropanamine, N-[(5-thiazolyl)methyl]-, dihydrochloride; 5-[(Cyclopropylamino)methyl]thiazole dihydrochloride; N-[(1,3-Thiazol-5-yl)methyl]cyclopropanamine dihydrochloride; N-(Thiazol-5-ylmethyl)cyclopropanamine dihydrochloride; 1332531-54-0; UNII-9F6F5I6J4C; AKOS025310999; CS-0475900
EINECS	Contact for details

Quality Control

Our n-(1,3-Thiazol-5-Ylmethyl)Cyclopropanaminedihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.