Description

Phenylacetyl-D5 L-Glutamine is a stable isotope-labeled analog of L-glutamine, where five hydrogen atoms are replaced by deuterium at the phenylacetyl moiety. This compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring high accuracy and reproducibility in analytical measurements. It is primarily required by researchers and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors for pharmacokinetic studies, metabolic research, and bioanalytical method development.

Application

• Internal standard for the quantitative LC-MS/MS analysis of L-glutamine and related metabolites in biological matrices.
• Use in stable isotope dilution mass spectrometry (SID-MS) for precise pharmacokinetic and pharmacodynamic studies.
• Tracer compound in metabolic flux analysis and research into glutamine metabolism in cell cultures and animal models.
• Critical reagent in the development and validation of GLP/GCP-compliant bioanalytical methods for drug development.
• Component in diagnostic assay kits for measuring amino acid levels in clinical samples.
• Research tool in neuroscience and oncology for studying the role of glutamine in cellular processes.

Basic Information

Product Name	Phenylacetyl-D5 L-Glutamine
CAS No.	1331909-01-3
Molecular Formula	C13H11D5N2O4
Molecular Weight	269.31 g/mol
Synonyms	N2-[(2,3,4,5,6-Pentadeuteriophenyl)acetyl]-L-glutamine; L-Glutamine, N-(phenyl-d5-acetyl)-; Phenyl-d5-acetyl-L-glutamine; Deuterated Phenylacetylglutamine; PAGln-d5; Internal Standard for Glutamine Analysis; Stable Isotope Labeled Glutamine Derivative
EINECS	Contact for details

Quality Control

Our Phenylacetyl-D5 L-Glutamine is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % D), chemical purity by HPLC, and confirmation of structure. We adhere to relevant standards for high-purity reference materials to support research and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.