Description

n-Methyl-1-(Methylthio)-2-Nitroethenamine-D3 is a deuterated isotopologue of a versatile nitroethenamine derivative, serving as a critical building block in advanced synthetic chemistry. Its primary value lies in its use as a labeled intermediate for the synthesis of deuterated compounds, enabling research and development in pharmacokinetics, metabolism studies, and analytical method development. This high-purity intermediate is essential for pharmaceutical R&D laboratories, agrochemical innovators, and specialized fine chemical manufacturers requiring stable isotope-labeled precursors for tracer applications and regulatory filings.

Application

• Deuterated Pharmaceutical Intermediate: Key synthon for incorporating deuterium into active pharmaceutical ingredients (APIs) for drug discovery and development.
• Metabolic Tracer Synthesis: Used in creating labeled compounds for mass spectrometry-based metabolism and pharmacokinetic (DMPK) studies.
• Agrochemical Research: Intermediate for developing novel, labeled agrochemicals and studying their environmental fate and degradation pathways.
• Analytical Reference Standard: Serves as a precursor for certified reference materials (CRMs) and internal standards in LC-MS and GC-MS analysis.
• Organic Synthesis Building Block: Utilized in complex organic transformations where its nitro and methylthio functional groups offer strategic reactivity.
• Isotope Labeling Services: A critical material for contract research organizations (CROs) and CDMOs offering custom deuterium labeling services.

Basic Information

Product Name	n-Methyl-1-(Methylthio)-2-Nitroethenamine-D3
CAS No.	1331637-53-6
Molecular Formula	C4H5D3N2O2S
Molecular Weight	151.19 g/mol
Synonyms	1-(Methylthio)-2-nitro-N-methylethenamine-D3; 2-Nitro-1-(methylthio)-N-methylethenamine-D3; N-Methyl-1-(methylthio)-2-nitroethenamine-d3; (E)-N-Methyl-1-(methylthio)-2-nitroethenamine-D3; Deuterated Nitroenamine; Methyl (methyl-D3-amino)(nitro)methylene sulfide; [D3]-N-Methyl-1-(methylthio)-2-nitroethenamine
EINECS	Contact for details

Quality Control

Our n-Methyl-1-(Methylthio)-2-Nitroethenamine-D3 is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including NMR (1H, 13C), mass spectrometry, and HPLC to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (D-content, MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.