Description

8-Amino-3-Boc-3-Azabicyclo[3.2.1]Octane CAS NO 1330763-51-3 is a high-value, protected bicyclic amine building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a key precursor for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Scaffold: Used to construct and explore novel chemical libraries based on the 3-azabicyclo[3.2.1]octane core, a privileged structure in drug discovery.
• Peptidomimetic Synthesis: Serves as a constrained, rigid amino acid analog for designing peptide-like molecules with enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Agrochemical Research: Used as an intermediate in the development of new, high-performance crop protection agents.
• Academic Research: A valuable reagent for synthetic methodology development and the study of bicyclic nitrogen-containing systems.

Basic Information

Product Name	8-Amino-3-Boc-3-Azabicyclo[3.2.1]Octane
CAS No.	1330763-51-3
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)-3-azabicyclo[3.2.1]octan-8-amine; 8-Amino-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.2.1]octane; tert-Butyl 8-amino-3-azabicyclo[3.2.1]octane-3-carboxylate; 3-Azabicyclo[3.2.1]octane-8-amine, 3-[(1,1-dimethylethoxy)carbonyl]-; 3-Boc-3-azabicyclo[3.2.1]octan-8-amine; 8-Amino-3-Boc-3-aza-bicyclo[3.2.1]octane; Bicyclic Boc-protected amine 1330763-51-3
EINECS	Contact for details

Quality Control

Our 8-Amino-3-Boc-3-Azabicyclo[3.2.1]Octane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and oxidatively sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.