Description

(5-Bromo-Isoquinolin-1-Yl)-Carbamic Acid tert-Butyl Ester CAS NO 1330754-23-8 is a high-purity, advanced pharmaceutical intermediate belonging to the isoquinoline class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for applications in oncology and central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• API Synthesis: Serves as a crucial building block in the production of complex Active Pharmaceutical Ingredients (APIs) for clinical trials and commercial manufacturing.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	(5-Bromo-Isoquinolin-1-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1330754-23-8
Molecular Formula	C14H15BrN2O2
Molecular Weight	323.19 g/mol
Synonyms	tert-Butyl (5-bromoisoquinolin-1-yl)carbamate; 1-Isoquinolinamine, 5-bromo-N-[(1,1-dimethylethoxy)carbonyl]-; N-Boc-5-bromo-1-aminoisoquinoline; 5-Bromo-1-[(tert-butoxycarbonyl)amino]isoquinoline; Boc-5-Bromo-1-aminoisoquinoline; 5-Bromo-1-N-Boc-aminoisoquinoline; (5-Bromo-1-isoquinolinyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (5-Bromo-Isoquinolin-1-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.