Description

2-(n-Benzyl-n-Methyl)Amino-2-Phenylbutanol-D5 is a deuterated analog of a chiral amino alcohol, serving as a critical building block in advanced pharmaceutical research and development. Its primary value lies in its use as a stable isotope-labeled internal standard for precise quantitative analysis in bioanalytical studies, ensuring accurate pharmacokinetic and metabolic profiling. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-fidelity analytical standards for method development and quality control of active pharmaceutical ingredients (APIs).

Application

• Internal Standard for LC-MS/MS: Used as a deuterium-labeled internal standard in Liquid Chromatography-Mass Spectrometry for the accurate quantification of its non-deuterated counterpart in complex biological matrices.
• Pharmaceutical Metabolite Studies: Enables tracking and quantification of drug metabolites in preclinical and clinical research, improving the understanding of drug metabolism and excretion pathways.
• Method Development and Validation: Critical for developing and validating robust bioanalytical methods in compliance with regulatory guidelines (e.g., FDA, EMA) for new drug applications.
• Pharmacokinetic (PK) and Pharmacodynamic (PD) Research: Provides reliable data on drug absorption, distribution, metabolism, and excretion (ADME) in vivo.
• Reference Material for Quality Control: Serves as a certified reference material to ensure the purity and consistency of pharmaceutical batches during manufacturing.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-precision IDMS techniques to achieve superior accuracy and minimize matrix effects in analytical measurements.

Basic Information

Product Name	2-(n-Benzyl-n-Methyl)Amino-2-Phenylbutanol-D5
CAS No.	1330265-76-3
Molecular Formula	C18H18D5NO
Molecular Weight	~274.4 g/mol
Synonyms	2-[(Benzyl)(methyl)amino]-2-phenylethanol-d5; 2-(Benzylmethylamino)-1-phenylethanol-d5; 2-(N-Benzyl-N-methylamino)-2-phenylethanol-d5; 2-Phenyl-2-[(phenylmethyl)methylamino]ethanol-d5; Deuterated BMAPE; Amino Alcohol-d5; Stable Isotope Labeled Amino Alcohol; (RS)-2-(Benzylmethylamino)-1-phenylethanol-d5
EINECS	Contact for details

Quality Control

Every batch of 2-(n-Benzyl-n-Methyl)Amino-2-Phenylbutanol-D5 is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and all specification results is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.