Description

Isothipendyl-D6 is a deuterium-labeled analog of the antihistamine Isothipendyl, specifically designed for use as an internal standard in quantitative analytical methods. This stable isotope-labeled compound is essential for ensuring accuracy and precision in mass spectrometry-based analyses, such as LC-MS/MS, by correcting for variations in sample preparation and instrument response. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, forensic toxicology, and clinical research sectors who require reliable and traceable analytical results.

Application

• Internal Standard for LC-MS/MS quantification of Isothipendyl in biological matrices (e.g., plasma, urine).
• Metabolite identification and pharmacokinetic studies in pharmaceutical R&D.
• Forensic analysis and toxicology screening for accurate drug level determination.
• Quality control and method validation in pharmaceutical manufacturing.
• Stable isotope dilution analysis (SIDA) to enhance analytical precision.
• Reference material for calibrating analytical instrumentation.

Basic Information

Product Name	Isothipendyl-D6
CAS No.	1330265-10-5
Molecular Formula	C16H13D6N3S
Molecular Weight	287.42 g/mol
Synonyms	10H-Pyrido[3,2-b][1,4]benzothiazine-10-ethanamine, N,N-dimethyl-, 2,3,4,5,6,7-hexadeuterio-; Isothipendyl hexadeuterated; Isothipendyl-d6; Deuterated Isothipendyl; [2H6]-Isothipendyl; N,N-Dimethyl-2-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)ethanamine-d6; Andantol-d6 (labeled analog)
EINECS	Contact for details

Quality Control

Our Isothipendyl-D6 is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment suitable for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC), isotopic purity (by MS), and residual solvent content. We adhere to relevant industry standards for reference materials, and custom synthesis to meet specific purity or enrichment specifications is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.