Description

4-[2-[Bis(1,1-Dideuteriopropyl)Amino]Ethyl]-1,3-Dihydroindol-2-One:Hydrochloride is a high-purity, deuterated organic compound primarily used as a critical intermediate or reference standard in advanced research and development. This compound is valued for its role in metabolic and pharmacokinetic studies, where deuterium labeling provides distinct analytical advantages. It is essential for pharmaceutical researchers, agrochemical developers, and contract research organizations (CROs) focused on drug discovery and material science.

Application

• Pharmaceutical Research: Key intermediate in the synthesis of deuterated drug candidates for improved metabolic stability and bioavailability studies.
• Metabolite Identification: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate quantification and tracing of metabolites.
• Pharmacokinetics (PK) & Pharmacodynamics (PD): Serves as a stable isotope-labeled tracer to study absorption, distribution, metabolism, and excretion (ADME) profiles.
• Agrochemical Development: Intermediate for creating novel, labeled active ingredients to study environmental fate and degradation pathways.
• Analytical Reference Standard: Provides a certified material for method development, validation, and quality control in analytical laboratories.
• Chemical Biology Probes: Building block for creating labeled probes to investigate biological mechanisms and protein interactions.

Basic Information

Product Name	4-[2-[Bis(1,1-Dideuteriopropyl)Amino]Ethyl]-1,3-Dihydroindol-2-One:Hydrochloride
CAS No.	1330261-37-4
Molecular Formula	C19H29D4ClN2O
Molecular Weight	352.95 g/mol (approx.)
Synonyms	4-[2-[Bis(1,1-Dideuteriopropyl)amino]ethyl]-2-indolinone hydrochloride; 2-Oxo-4-[2-[bis(1,1-dideuteriopropyl)amino]ethyl]indoline hydrochloride; Deuterated Indolinone Propylamine Hydrochloride; 1330261-37-4; 4-(2-(Bis(1,1-dideuteriopropyl)amino)ethyl)-1,3-dihydro-2H-indol-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[2-[Bis(1,1-Dideuteriopropyl)Amino]Ethyl]-1,3-Dihydroindol-2-One:Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content, MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.