Description

Hydroxy Tyrosol-D4 is a deuterium-labeled isotopologue of the natural phenolic antioxidant hydroxytyrosol, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, where it corrects for variations in sample preparation and instrument response. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and food science industries who require precise quantification of hydroxytyrosol and related metabolites.

Application

• Quantitative Mass Spectrometry: Serves as a stable isotope-labeled internal standard for the accurate LC-MS/MS and GC-MS quantification of hydroxytyrosol in complex biological matrices (e.g., plasma, urine, tissue).
• Pharmacokinetic and Metabolic Studies: Enables precise tracking of hydroxytyrosol absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Food and Beverage Analysis: Used for the standardized measurement of hydroxytyrosol content in olive oil, olive leaf extracts, and other functional foods to verify label claims and antioxidant potency.
• Nutraceutical Quality Control: Critical for assaying the active ingredient concentration in dietary supplements and herbal extracts containing hydroxytyrosol.
• Biomarker Research: Facilitates the development of robust assays for hydroxytyrosol as a potential biomarker of olive product consumption or oxidative stress status.
• Method Development and Validation: Provides a reference standard for developing, optimizing, and validating new analytical methods in compliance with ICH and FDA guidelines.

Basic Information

Product Name	Hydroxy Tyrosol-D4
CAS No.	1330260-89-3
Molecular Formula	C8H6D4O3
Molecular Weight	158.19 g/mol
Synonyms	3,4-Dihydroxyphenethyl-1,1,2,2-d4-ol; 4-(2-Hydroxyethyl)-1,2-benzenediol-d4; 2-(3,4-Dihydroxyphenyl)ethanol-d4; D4-Hydroxytyrosol; [2H4]-Hydroxytyrosol; Deuterated Hydroxytyrosol; 3-Hydroxytyrosol-d4; Internal Standard for Hydroxytyrosol
EINECS	Contact for details

Quality Control

Every batch of Hydroxy Tyrosol-D4 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure the highest standards of isotopic purity and chemical identity. Our quality commitment includes comprehensive characterization by NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for isotopic enrichment, chemical purity, and absence of interfering impurities, supporting your compliance with GLP and GMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.