Description

2-[2-[2,2,3,3,5,5,6,6-Octadeuterio-4-(11-Oxobenzo[B][1,4]Benzothiazepin-6-Yl)Piperazin-1-Yl]Ethoxy]Ethanol is a deuterated derivative of a benzothiazepinone-piperazine compound, serving as a critical stable isotope-labeled standard. This compound is essential for advanced analytical research, providing unmatched precision in quantitative analysis and metabolic studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug discovery and development.

Application

• Internal Standard for LC-MS/MS: Used as a deuterium-labeled internal standard in liquid chromatography-tandem mass spectrometry for the accurate quantification of the parent drug and its metabolites in biological matrices.
• Pharmacokinetic & Metabolic Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Bioanalytical Method Development & Validation: Critical for developing and validating robust, sensitive, and specific analytical methods compliant with FDA and ICH guidelines.
• Drug Impurity Profiling: Assists in the identification and quantification of process-related impurities and degradation products during drug substance and product development.
• Stable Isotope Dilution Assays: Employed in assays where the deuterated analog compensates for matrix effects and analyte loss, ensuring high data accuracy and reproducibility.

Basic Information

Product Name	2-[2-[2,2,3,3,5,5,6,6-Octadeuterio-4-(11-Oxobenzo[B][1,4]Benzothiazepin-6-Yl)Piperazin-1-Yl]Ethoxy]Ethanol
CAS No.	1330238-38-4
Molecular Formula	C23H22D8N3O3S
Molecular Weight	Contact for details
Synonyms	Deuterated Benzothiazepinone-Piperazine Ethanol Derivative; 2-[2-[4-(11-Oxobenzo[b][1,4]benzothiazepin-6-yl)piperazin-1-yl]ethoxy]ethanol-d8; 6-[4-[2-(2-Hydroxyethoxy)ethyl]piperazin-1-yl]benzo[b][1,4]benzothiazepin-11-one-d8; Stable Isotope-Labeled Internal Standard (d8); (11-Oxo-6-piperazinylbenzo[b][1,4]benzothiazepin-2-ylethoxy)ethanol-d8; Deuterated Analytical Standard; CAS 1330238-38-4
EINECS	Contact for details

Quality Control

Our deuterated standards are produced under strict quality management systems to ensure the highest isotopic purity and chemical integrity. Each batch undergoes comprehensive analysis, including HPLC, NMR, and MS, to confirm identity, chemical purity, and isotopic enrichment. Certificates of Analysis (COA) detailing lot-specific data are provided and are traceable to primary reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at -20°C under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (d8)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.