Description

3-Chloro-2-Methylbiphenyl-D5 is a deuterated analog of 3-chloro-2-methylbiphenyl, where five hydrogen atoms are replaced with the stable isotope deuterium. This compound is primarily valued as a high-purity internal standard and reference material for analytical quantification, particularly in mass spectrometry, due to its isotopic labeling which minimizes matrix interference. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing sectors who require precise and reliable analytical methods for trace-level detection and quantification of its non-deuterated counterpart.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a critical component in LC-MS and GC-MS methods for the accurate quantification of 3-chloro-2-methylbiphenyl in complex matrices.
• Pharmaceutical Impurity Profiling: Serves as a reference standard in the analysis and control of potential genotoxic impurities (PGIs) in active pharmaceutical ingredients (APIs).
• Metabolite Studies: Employed in drug metabolism and pharmacokinetics (DMPK) research as a stable isotope-labeled tracer to study biotransformation pathways.
• Environmental Analysis: Facilitates the detection and monitoring of biphenyl derivatives and related chlorinated compounds in environmental samples.
• Agrochemical Research: Acts as a key analytical standard in the development and validation of methods for pesticide residue analysis.
• Chemical Synthesis Research: Used in mechanistic studies and as a labeled building block in synthetic chemistry for tracking reactions.

Basic Information

Product Name	3-Chloro-2-Methylbiphenyl-D5
CAS No.	1330173-04-0
Molecular Formula	C13H4D5Cl
Molecular Weight	203.71 g/mol (approx.)
Synonyms	2-Methyl-3-chlorobiphenyl-D5; 1-Chloro-2-methyl-1,1'-biphenyl-D5; 3-Chloro-2-methyl-1,1'-biphenyl-D5; Biphenyl, 3-chloro-2-methyl-, pentadeutero-; Deuterated 3-Chloro-2-Methylbiphenyl; [D5]-3-Chloro-2-Methylbiphenyl; 3-Chloro-2-Methylbiphenyl (phenyl-D5); (2-Methyl-3-chlorophenyl)benzene-D5
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Methylbiphenyl-D5 is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D-enrichment), chemical purity by HPLC, and identity confirmation. We adhere to relevant industry standards for reference materials, and custom purity grades or specific analytical data packages are available to meet your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The product is stable under these conditions for extended periods.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.