Description

4-(4-Aminophenyl)-3-Morpholinone-D4 is a deuterated derivative of a key aromatic amine-morpholinone compound, where four hydrogen atoms are replaced with deuterium. This deuteration provides enhanced molecular stability and is critical for applications requiring precise isotopic labeling, such as in analytical method development and metabolic studies. It serves as a valuable intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly in the synthesis of deuterated active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Deuterated Pharmaceutical Intermediate: Used in the synthesis of deuterium-labeled drug candidates to improve metabolic stability and for pharmacokinetic studies.
• Internal Standard for Mass Spectrometry: Serves as a high-purity internal standard in LC-MS and GC-MS analysis for accurate quantification of its non-deuterated counterpart in complex matrices.
• Metabolic Pathway Tracing: Employed in research to trace and elucidate metabolic pathways and degradation products in biological systems.
• Agrochemical Research: Acts as a building block for developing novel, isotopically labeled agrochemicals and studying their environmental fate.
• Material Science Research: Utilized in the development of specialty polymers and advanced organic electronic materials where isotopic purity affects performance.
• Chemical Reference Standard: Provides a certified reference material for quality control and regulatory compliance in analytical laboratories.

Basic Information

Item	Details
Product Name	4-(4-Aminophenyl)-3-Morpholinone-D4
CAS No.	1329837-80-0
Molecular Formula	C10H8D4N2O2
Molecular Weight	~196.23 g/mol
Synonyms	4-(4-Aminophenyl)-3-morpholinone-2,2,5,5-d4; 3-Morpholinone, 4-(4-aminophenyl)-, 2,2,5,5-d4; Deuterated 4-(4-Aminophenyl)morpholin-3-one; 4-(4-Aminophenyl)-3-morpholinone (D4); APM-D4; [2,2,5,5-2H4]-4-(4-Aminophenyl)-3-morpholinone; 4-(4-Aminophenyl)-2,2,5,5-tetradeuterio-3-morpholinone
EINECS	Contact for details

Quality Control

Our 4-(4-Aminophenyl)-3-Morpholinone-D4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high isotopic purity and chemical identity. We provide a detailed Certificate of Analysis (COA) that includes results for assay, isotopic enrichment (D-content), and impurity profile by HPLC and NMR. Our quality commitment supports applications in regulated environments, including pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.