Description

n-Acetyl-n-tert-Butoxycarbonyl Serotonin is a key, protected derivative of the essential neurotransmitter serotonin, designed for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring a stable, reactive intermediate with orthogonal protecting groups for selective deprotection. It is primarily utilized in the pharmaceutical and life sciences sectors for the development of novel therapeutic agents and biochemical research tools.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Biochemical Research: Used in proteomics and neuroscience research to study serotonin pathways, receptor binding, and enzyme interactions.
• Peptide Synthesis: Serves as a protected serotonin moiety for the solid-phase or solution-phase synthesis of bioactive peptides and peptidomimetics.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Chemical Biology Probes: Facilitates the creation of labeled probes for imaging and diagnostic applications.

Basic Information

Product Name	n-Acetyl-n-tert-Butoxycarbonyl Serotonin
CAS No.	1329837-64-0
Molecular Formula	C18H24N2O5
Molecular Weight	348.40 g/mol
Synonyms	5-HT-Boc-Ac; N-Acetyl-N-Boc-serotonin; N-Boc-N-acetylserotonin; Serotonin, N-acetyl-, N-Boc derivative; 5-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide, N-Boc protected; 2-({[tert-Butoxy)carbonyl][2-(5-hydroxy-1H-indol-3-yl)ethyl]amino}ethyl acetate; N-tert-Butoxycarbonyl-N-acetyl-5-hydroxytryptamine
EINECS	Contact for details

Quality Control

Our n-Acetyl-n-tert-Butoxycarbonyl Serotonin is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.