Description

Dansyl Acid-D6 is a deuterium-labeled derivative of dansyl chloride, a cornerstone reagent in analytical chemistry. This stable isotope-labeled compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry analyses, serving as an internal standard to correct for variations in sample preparation and instrument response. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and environmental monitoring sectors who require precise quantification of amines, amino acids, and other dansylatable compounds.

Application

• Internal Standard for LC-MS/MS: Primary use as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the analysis of biogenic amines, neurotransmitters (e.g., serotonin, dopamine), and amino acids.
• Proteomics and Metabolomics Research: Enables accurate relative and absolute quantification in high-throughput profiling studies of proteins and metabolites.
• Pharmaceutical Bioanalysis: Critical for the precise pharmacokinetic (PK) and pharmacodynamic (PD) studies of drug candidates and their metabolites in biological matrices.
• Food and Beverage Analysis: Used in the quantification of amino acids, biogenic amines (e.g., histamine), and other markers for quality control and safety assessment.
• Clinical Diagnostics: Supports the development and validation of diagnostic assays for inborn errors of metabolism and other conditions based on small molecule biomarkers.
• Environmental Monitoring: Applicable in trace analysis of amine-based pollutants or degradation products in environmental samples.

Basic Information

Product Name	Dansyl Acid-D6
CAS No.	1329836-02-3
Molecular Formula	C12H6D6NO3S
Molecular Weight	256.33 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonic Acid-d6; Dansyl-D6 Acid; DNS Acid-d6; 1-Dimethylaminonaphthalene-5-sulfonic Acid-d6; DANSYL-D6; Deuterated Dansyl Acid; [2H6]-Dansyl Acid; 5-(Dimethyl-d6-amino)naphthalene-1-sulfonic Acid
EINECS	Contact for details

Quality Control

Our Dansyl Acid-D6 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and Mass Spectrometry to confirm isotopic enrichment and chemical purity, and HPLC to determine chemical and isomeric purity. Certificates of Analysis (COA) detailing batch-specific results are provided and traceable to relevant high-purity reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (NMR)	Conforms to structure
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.