Description

2-Methyl-3-Phenylbenzoic Acid-D5 Methyl Ester is a high-purity, deuterated internal standard critical for ensuring analytical accuracy in quantitative mass spectrometry. This stable isotope-labeled compound is essential for researchers and quality control laboratories requiring precise quantification of its non-deuterated counterpart. It is primarily utilized in pharmaceutical development, forensic toxicology, and advanced material science research where method validation and regulatory compliance are paramount.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical method development and validation for pharmacokinetic studies.
• Pharmaceutical Impurity Profiling: Enables accurate tracking and quantification of process-related impurities and degradation products during drug development.
• Metabolite Studies: Facilitates the precise measurement of drug metabolites in complex biological matrices like plasma, urine, and tissue homogenates.
• Forensic and Clinical Toxicology: Serves as a critical component in assays for the accurate detection and quantification of specific analytes in forensic investigations.
• Environmental Analysis: Applied in method development for tracking specific organic compounds in environmental samples.
• Isotope Dilution Mass Spectrometry (IDMS): The gold-standard technique for achieving highest accuracy and traceability in chemical measurement.

Basic Information

Product Name	2-Methyl-3-Phenylbenzoic Acid-D5 Methyl Ester
CAS No.	1329835-46-2
Molecular Formula	C15H9D5O2
Molecular Weight	~235.29 g/mol
Synonyms	2-Methyl-3-phenylbenzoic acid methyl ester-d5; Methyl 2-methyl-3-phenylbenzoate-d5; 3-Phenyl-o-toluic acid methyl ester-d5; Benzoic acid, 2-methyl-3-phenyl-, methyl ester-d5; Deuterated 2-Methyl-3-Phenyl Methyl Benzoate; [D5]-Methyl 2-methyl-3-phenylbenzoate; Internal Standard for 2-Methyl-3-phenylbenzoic acid; Stable Isotope Labeled Analog (SILA)
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-3-Phenylbenzoic Acid-D5 Methyl Ester is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR (1H, 13C), Mass Spectrometry, and HPLC. A Certificate of Analysis (COA) detailing purity, isotopic enrichment (D5, atom % D), and solvent content is provided with each shipment to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (D5)
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.