Description

Benzoctamine-D3 Hydrochloride is a deuterated isotopologue of the pharmaceutical compound Benzoctamine, specifically labeled with three deuterium atoms. This high-purity reference standard is essential for precise analytical quantification and metabolic studies, ensuring data accuracy and reliability in research and development. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in pharmacokinetics, drug metabolism, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a critical, non-interfering reference for the accurate quantification of Benzoctamine in complex biological matrices like plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used to trace and elucidate metabolic pathways, absorption, distribution, and excretion profiles of the parent drug.
• Bioanalytical Method Development and Validation: Provides a stable isotopic label to optimize and validate sensitive and specific analytical methods, improving precision and accuracy.
• Clinical Research and Therapeutic Drug Monitoring (TDM): Enables precise measurement of drug concentrations in patient samples to ensure therapeutic efficacy and safety.
• Pharmaceutical Quality Control: Acts as a reference material for impurity profiling and assay development of active pharmaceutical ingredients (APIs) and finished dosage forms.

Basic Information

Product Name	Benzoctamine-D3 Hydrochloride
CAS No.	1329833-52-4
Molecular Formula	C19H19D3N2O•HCl
Molecular Weight	334.87 g/mol (approx.)
Synonyms	Benzoctamine-d3 HCl; 2-[(2-Octylamino)ethyl]benzo[d]isothiazole-1,1-dioxide-d3 Hydrochloride; N-Ethyl-2-(octylamino)-1,2-benzisothiazol-3(2H)-one 1,1-Dioxide-d3 Hydrochloride; TACITIN-d3 Hydrochloride; Benzoctamine (phenyl-d3) Hydrochloride; Deuterated Benzoctamine HCl; Benzoctamine Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Benzoctamine-D3 Hydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical and isotopic purity, supported by a detailed Certificate of Analysis (COA) that includes results from NMR, HPLC, and MS. Our quality commitment ensures the material meets the stringent requirements for use as a certified reference standard in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 99.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.