Description

(4S,αs)-4-Benzyl-3-(α-Methyl-1-Oxohexyl)-2-Oxazolidinone-D3 is a high-purity, deuterium-labeled chiral auxiliary and synthetic intermediate. This compound is critical for enabling precise stereochemical control and isotopic tracing in advanced pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and for conducting detailed metabolic studies.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Employed to induce high enantioselectivity in key carbon-carbon and carbon-heteroatom bond-forming reactions.
• Deuterium-Labeled Intermediate: Used in the synthesis of deuterated drug candidates for pharmacokinetic (PK), pharmacodynamic (PD), and mass spectrometry studies.
• Pharmaceutical Process Research: Serves as a crucial building block in the development and scale-up of synthetic routes for complex, stereochemically defined molecules.
• Metabolic Pathway Tracing: The deuterium label allows for the tracking of a compound's fate in biological systems, aiding in drug metabolism and safety assessments.
• Reference Standard: Can be used as an analytical standard for quality control and method validation in laboratories producing or using similar compounds.

Basic Information

Product Name	(4S,αs)-4-Benzyl-3-(α-Methyl-1-Oxohexyl)-2-Oxazolidinone-D3
CAS No.	1329812-07-8
Molecular Formula	C₁₈H₂₂D₃NO₃
Molecular Weight	~304.42 g/mol
Synonyms	(4S)-4-Benzyl-3-[(2S)-2-methyl-1-oxohexyl]-1,3-oxazolidin-2-one-d3; (4S,2'S)-4-Benzyl-3-(2'-methylhexanoyl)-2-oxazolidinone-d3; Evans Auxiliary derivative-d3; Deuterated N-Benzyloxycarbonyl-α-methylnorleucine Oxazolidinone; N-[(Benzyloxy)carbonyl]-α-methyl-D3-norleucine Oxazolidinone; (S)-4-Benzyl-3-((S)-2-methyl-1-oxohexyl)oxazolidin-2-one-d3; Chiral Oxazolidinone Auxiliary-d3
EINECS	Contact for details

Quality Control

Our (4S,αs)-4-Benzyl-3-(α-Methyl-1-Oxohexyl)-2-Oxazolidinone-D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and isotopic enrichment analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (by HPLC), chiral purity, deuterium content, and related substances is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.