Description

2,2-Dideuterio-2-(2,2,3,3,4,4-Hexadeuterio-5-Oxopyrrolidin-1-Yl)Acetamide is a high-purity, deuterium-labeled chemical compound, also known by its CAS number 1329799-64-5. This compound is specifically designed for use as a stable isotope-labeled internal standard in advanced analytical chemistry, providing critical accuracy and reliability in quantitative mass spectrometry. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, agrochemical, and metabolomics fields who require precise measurement of target analytes.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard in Liquid Chromatography-Tandem Mass Spectrometry for the accurate quantification of pharmaceutical compounds and their metabolites.
• Biomedical Research: Enables precise tracking and measurement in pharmacokinetic, pharmacodynamic, and drug metabolism studies.
• Metabolomics and Proteomics: Facilitates the identification and quantification of biomarkers and small molecules in complex biological samples.
• Pharmaceutical Development: Critical for method validation, ensuring regulatory compliance in drug development and manufacturing quality control.
• Environmental and Food Safety Testing: Applied in the detection and quantification of trace-level contaminants and residues.
• Isotope Dilution Mass Spectrometry (IDMS): Serves as the labeled spike in IDMS, the gold-standard technique for achieving high metrological accuracy.

Basic Information

Product Name	2,2-Dideuterio-2-(2,2,3,3,4,4-Hexadeuterio-5-Oxopyrrolidin-1-Yl)Acetamide
CAS No.	1329799-64-5
Molecular Formula	C6H5D8N2O2
Molecular Weight	177.25 g/mol
Synonyms	1-(2-Acetamido-1,1-dideuterioacetyl)-5-oxopyrrolidine-2,2,3,3,4,4-hexadeuterio; Deuterated N-Acetyl-2-pyrrolidinone Acetamide; D8-2-Pyrrolidinone, 1-(2-acetamido-1,1-d2-acetyl)-; 1-[2-(Acetylamino)-1,1-dideuterioacetyl]-2-pyrrolidinone-d8; Perdeuterated N-Acetyl-2-pyrrolidinone Acetamide Derivative; Stable Isotope Labeled Internal Standard 1329799-64-5
EINECS	Contact for details

Quality Control

Our 2,2-Dideuterio-2-(2,2,3,3,4,4-Hexadeuterio-5-Oxopyrrolidin-1-Yl)Acetamide is manufactured under strict quality systems to ensure the high isotopic purity and chemical integrity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D%), chemical purity, and impurity profiles as determined by NMR, HPLC, and LC-MS. We adhere to cGMP principles where applicable to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D%)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.