Description

3-(Dimethyl-D6-Amino)-4'-Bromopropiophenone is a deuterated organic compound featuring a brominated propiophenone core with a dimethylamino group, where the methyl groups are fully substituted with deuterium (D6). This deuteration makes it a valuable stable isotope-labeled standard, crucial for enhancing the accuracy and reliability of analytical methods. It is primarily utilized by research and development laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications such as quantitative mass spectrometry, metabolic studies, and as an internal standard for pharmacokinetic research.

Application

• Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for precise quantification.
• Critical in pharmaceutical research for drug metabolism and pharmacokinetics (DMPK) studies, aiding in the understanding of absorption, distribution, metabolism, and excretion (ADME).
• Employed in the development and validation of analytical methods to ensure regulatory compliance and data integrity.
• Applied in forensic and clinical toxicology for the accurate detection and measurement of target analytes in complex biological matrices.
• Serves as a key intermediate or reference material in the synthesis of deuterated analogs of more complex bioactive molecules.
• Facilitates research in environmental analysis for tracing the fate and transformation of chemical pollutants.

Basic Information

Product Name	3-(Dimethyl-D6-Amino)-4'-Bromopropiophenone
CAS No.	1329796-42-0
Molecular Formula	C11H7D6BrNO
Molecular Weight	272.18 g/mol (approx.)
Synonyms	4'-Bromo-3-(dimethylamino)propiophenone-D6; 1-(4-Bromophenyl)-3-(dimethylamino)-1-propanone-D6; 3-(Dimethylamino)-4'-bromopropiophenone-D6; Deuterated Bupropion Impurity/Intermediate; 4'-Bromopropiophenone-D6 dimethylamino derivative; (Dimethyl-d6-amino)(4-bromophenyl)propan-1-one; 3-(N,N-Dimethyl-d6-amino)-1-(4-bromophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Every batch of 3-(Dimethyl-D6-Amino)-4'-Bromopropiophenone is manufactured and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with specifications typically meeting or exceeding the requirements for analytical reference standards. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as assay, isotopic enrichment (D6), and impurity profile by HPLC and NMR. Our quality system is designed to support GMP/GLP-compliant research and ensure traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under optimal conditions, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D6)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.