Description

4-(2-Bromophenyl)-2,6-Dimethyl-3,5-Pyridinedicarboxylic Acid-D10 Diethyl Ester is a high-purity, deuterium-labeled (D10) derivative of a key pyridinedicarboxylate intermediate. This compound is specifically designed for use as an internal standard in advanced analytical techniques, providing superior accuracy and reliability in quantitative analysis. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and material science sectors who require precise measurement and traceability in method development and regulatory compliance.

Application

• Internal Standard for LC-MS/MS: Primary application as a stable isotope-labeled internal standard for the accurate quantification of its non-deuterated counterpart or related metabolites in complex biological matrices.
• Pharmaceutical Research & Development: Critical for pharmacokinetic (PK), pharmacodynamic (PD), and bioanalytical studies to ensure data integrity and meet regulatory standards (e.g., FDA, EMA).
• Metabolite Identification & Profiling: Used in drug metabolism studies to track and quantify drug-derived compounds, aiding in the understanding of metabolic pathways.
• Agrochemical Analysis: Supports the development and validation of analytical methods for the detection and quantification of pesticides or their degradation products in environmental and food safety testing.
• Chemical Synthesis Intermediate: Serves as a specialized, labeled building block for the synthesis of novel deuterated compounds for research purposes.
• Forensic & Clinical Toxicology: Enhances the precision of assays designed to detect specific chemical entities in forensic or clinical samples.

Basic Information

Product Name	4-(2-Bromophenyl)-2,6-Dimethyl-3,5-Pyridinedicarboxylic Acid-D10 Diethyl Ester
CAS No.	1329793-25-0
Molecular Formula	C20H15D10BrNO4
Molecular Weight	~437.4 g/mol
Synonyms	Diethyl 4-(2-bromophenyl)-2,6-dimethyl-3,5-pyridinedicarboxylate-D10; 3,5-Pyridinedicarboxylic acid, 4-(2-bromophenyl)-2,6-dimethyl-, diethyl ester, D10-labeled; Deuterated 4-(2-Bromophenyl)-2,6-Dimethyl-3,5-Pyridinedicarboxylic Acid Diethyl Ester; D10-Labeled Pyridinedicarboxylate Ester; 4-(2-Bromophenyl)-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester (D10); Stable Isotope Labeled Internal Standard 1329793-25-0
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality systems to ensure the high isotopic purity and chemical integrity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment (D10), chemical purity, and analytical results. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D10)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.