Description

2-Methylsulfonyl-10-[2-[1-(Trideuteriomethyl)Piperidin-2-Yl]Ethyl]Phenothiazine is a deuterated phenothiazine derivative, a high-value specialty chemical designed for advanced research and development. This compound is critical for applications requiring stable isotope labeling, offering enhanced metabolic stability and traceability in pharmacokinetic and pharmacodynamic studies. It is primarily utilized by pharmaceutical R&D teams and contract research organizations (CROs) engaged in the development of novel therapeutics, particularly in the fields of neuroscience and central nervous system (CNS) drug discovery.

Application

• As a deuterated internal standard for the precise quantification of related phenothiazine compounds in bioanalytical methods using LC-MS/MS.
• In pharmaceutical research for the synthesis of deuterium-labeled drug candidates to study metabolic pathways and improve drug half-life.
• For mechanistic studies in medicinal chemistry, leveraging the kinetic isotope effect (KIE) to investigate reaction mechanisms and enzyme interactions.
• As a key advanced intermediate in the development of novel radiopharmaceuticals or PET tracer molecules.
• In academic and institutional research focusing on neurochemical pathways and receptor binding studies.

Basic Information

Product Name	2-Methylsulfonyl-10-[2-[1-(Trideuteriomethyl)Piperidin-2-Yl]Ethyl]Phenothiazine
CAS No.	1329652-09-6
Molecular Formula	C21H24D3N2O2S2
Molecular Weight	406.61 g/mol
Synonyms	10-[2-[1-(Trideuteriomethyl)-2-piperidinyl]ethyl]-2-(methylsulfonyl)phenothiazine; Deuterated Trifluoperazine Sulfone Derivative; 2-(Methylsulfonyl)-10-[2-(1-(trideuteriomethyl)piperidin-2-yl)ethyl]phenothiazine; Phenothiazine, 10-[2-[1-(trideuteriomethyl)-2-piperidinyl]ethyl]-2-(methylsulfonyl)-; Deuterium Labeled Phenothiazine Sulfone; CD3-Labeled Piperidine Phenothiazine
EINECS	Contact for details

Quality Control

Every batch of 2-Methylsulfonyl-10-[2-[1-(Trideuteriomethyl)Piperidin-2-Yl]Ethyl]Phenothiazine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and isotopic enrichment meet the exacting standards required for research use. Certificates of Analysis (COA) detailing results from NMR (1H, 13C), HPLC, and MS are available upon request, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.