Description

7-[1,1,2,2,3,3,3-Heptadeuteriopropyl(Propyl)Amino]-5,6,7,8-Tetrahydronaphthalen-1-Ol:Hydrobromide is a deuterated organic compound, specifically a hydrobromide salt of a deuterium-labeled tetrahydronaphthalenol derivative. This compound is of significant value as a stable isotope-labeled internal standard for analytical chemistry, enabling precise quantification and method validation in complex matrices. It is primarily needed by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical service providers engaged in pharmacokinetic studies, drug metabolism research, and high-precision bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Used as a deuterium-labeled analog for the accurate quantification of its non-deuterated counterpart in bioanalytical assays (e.g., plasma, serum, tissue homogenates).
• Drug Metabolism and Pharmacokinetics (DMPK): Essential for studying the absorption, distribution, metabolism, and excretion (ADME) profiles of pharmaceutical candidates.
• Method Development and Validation: Serves as a critical reference material to establish specificity, accuracy, precision, and recovery in analytical procedures.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-precision quantitative analysis to correct for sample preparation losses and instrument variability.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities or degradation products.
• Clinical Research: Supports therapeutic drug monitoring (TDM) and clinical trial sample analysis where high accuracy is mandated.

Basic Information

Item	Details
Product Name	7-[1,1,2,2,3,3,3-Heptadeuteriopropyl(Propyl)Amino]-5,6,7,8-Tetrahydronaphthalen-1-Ol:Hydrobromide
CAS No.	1329613-23-1
Molecular Formula	C₁₆H₂₀D₇BrNO
Molecular Weight	Contact for details
Synonyms	7-[(1,1,2,2,3,3,3-Heptadeuteriopropyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide; Deuterated Tetrahydronaphthalenol Hydrobromide; 7-(Heptadeuteriopropyl(propyl)amino)-1,2,3,4-tetrahydronaphthalen-1-ol HBr; 7-[(Propyl-d7)(propyl)amino]-5,6,7,8-tetrahydro-1-naphthol hydrobromide; 1-Naphthol, 5,6,7,8-tetrahydro-7-[(1,1,2,2,3,3,3-heptadeuteriopropyl)propylamino]-, hydrobromide; Deuterium-labeled Internal Standard 1329613-23-1; [D7]-Labeled Compound 1329613-23-1
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality management to ensure isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR (¹H, ¹³C), high-resolution mass spectrometry (HRMS), and HPLC. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as chemical purity, isotopic enrichment (D-content), and chromatographic profile. We support compliance with ICH Q2(R1) guidelines for analytical method validation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.