Description

2-(2-Chloroethoxy)-n-(4-Nitrophenyl)Acetamide-D4 is a deuterated isotopologue of a key chemical intermediate, where four hydrogen atoms are replaced with deuterium, providing a stable, non-radioactive label. This compound is essential for applications requiring precise tracking and analysis in research and development, offering enhanced mass spectrometry signal detection and metabolic stability. It is primarily utilized by pharmaceutical R&D laboratories and analytical service providers for use as an internal standard in quantitative LC-MS/MS analysis, drug metabolism and pharmacokinetics (DMPK) studies, and in the synthesis of labeled active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Quantitative Bioanalysis (LC-MS/MS)
• Metabolite Identification and Drug Metabolism Studies (DMPK)
• Tracer Compound in Pharmacokinetic and Pharmacodynamic Research
• Synthesis of Deuterium-Labeled Active Pharmaceutical Ingredients (APIs)
• Use in Environmental Fate Studies and Analytical Method Development
• Reference Material for Spectroscopic Calibration (NMR, MS)

Basic Information

Product Name	2-(2-Chloroethoxy)-n-(4-Nitrophenyl)Acetamide-D4
CAS No.	1329612-84-1
Molecular Formula	C10H7D4ClN2O4
Molecular Weight	271.70 g/mol (deuterated form)
Synonyms	N-(4-Nitrophenyl)-2-(2-chloroethoxy)acetamide-d4; 2-(2-Chloroethoxy)-N-(4-nitrophenyl)acetamide-d4; Deuterated 2-(2-Chloroethoxy)acet-4-nitroanilide; Acetamide, 2-(2-chloroethoxy)-N-(4-nitrophenyl)-, d4-; 2-(2-Chloroethoxy)-N-(4-nitrophenyl)acetamide (tetradeuterated); [D4]-2-(2-Chloroethoxy)-N-(4-nitrophenyl)acetamide
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control to ensure high chemical and isotopic purity, critical for reliable analytical results. Each batch is characterized by advanced spectroscopic techniques including NMR and Mass Spectrometry to confirm deuteration level and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), isotopic enrichment, and other relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.