Description

(4S,5S)-4-Methyl-5-Phenyl-3-(Trideuteriomethyl)-1,3-Oxazolidin-2-One CAS NO 1329610-93-6 is a high-purity, deuterated chiral oxazolidinone derivative. This compound serves as a crucial chiral auxiliary and building block in advanced asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Asymmetric Synthesis: Acts as a chiral auxiliary for the stereoselective alkylation, aldol, and Diels-Alder reactions.
• Pharmaceutical Intermediate: Key building block in the research and development of enantiomerically pure drug candidates.
• Deuterated Compound Synthesis: The trideuteriomethyl group makes it valuable for creating deuterium-labeled compounds used in metabolic studies and as internal standards.
• Catalyst and Ligand Precursor: Used in the preparation of chiral catalysts and ligands for homogeneous catalysis.
• Academic and Industrial R&D: Essential reagent for methodological development in organic chemistry and process chemistry optimization.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(4S,5S)-4-Methyl-5-Phenyl-3-(Trideuteriomethyl)-1,3-Oxazolidin-2-One
CAS No.	1329610-93-6
Molecular Formula	C12H12D3NO2
Molecular Weight	208.26 g/mol
Synonyms	(4S,5S)-4-Methyl-5-phenyl-3-(trideuteriomethyl)-2-oxazolidinone; (4S,5S)-3-(Trideuteriomethyl)-4-methyl-5-phenyl-1,3-oxazolidin-2-one; (4S,5S)-4-Methyl-5-phenyl-3-(methyl-d3)-2-oxazolidinone; Deuterated Evans Auxiliary; d3-Evans Oxazolidinone; (4S,5S)-4-Methyl-5-phenyl-3-(CD3)-2-oxazolidinone; (4S-cis)-4-Methyl-5-phenyl-3-(trideuteriomethyl)-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (4S,5S)-4-Methyl-5-Phenyl-3-(Trideuteriomethyl)-1,3-Oxazolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Deuterium Incorporation (MS/NMR)	≥ 98 atom % D
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.