Description

6,6,7,7,8,8-Hexadeuterio-5,9-Dihydrotetrazolo[1,5-A]Azepine is a deuterated derivative of a tetrazoloazepine scaffold, a compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its utility as a stable isotope-labeled internal standard or a metabolic probe, enabling precise quantification and detailed mechanistic studies in complex biological matrices. This high-purity specialty chemical is essential for researchers and developers in pharmaceutical, agrochemical, and analytical chemistry sectors who require reliable tools for mass spectrometry, pharmacokinetics, and drug metabolism research.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of its non-deuterated counterpart in bioanalytical methods using LC-MS/MS.
• In pharmacokinetic (PK) and drug metabolism studies to trace metabolic pathways and assess the stability of drug candidates.
• For use in deuterium exchange experiments to investigate reaction mechanisms and molecular interactions.
• As a key advanced intermediate in the synthesis of novel, deuterated pharmaceutical compounds aimed at improving metabolic stability.
• In academic and industrial research focused on the biological activity and properties of tetrazoloazepine-based molecules.
• For the development and validation of regulatory-grade analytical methods in compliance with GLP and GMP standards.

Basic Information

Product Name	6,6,7,7,8,8-Hexadeuterio-5,9-Dihydrotetrazolo[1,5-A]Azepine
CAS No.	1329509-68-3
Molecular Formula	C6D6N6
Molecular Weight	162.20 g/mol
Synonyms	5,9-Dihydrotetrazolo[1,5-a]azepine-6,6,7,7,8,8-d6; Hexadeuterated 5,9-Dihydrotetrazolo[1,5-a]azepine; Tetrazolo[1,5-a]azepine-d6; Deuterated Tetrazoloazepine; 6,6,7,7,8,8-d6-5H,9H-Tetrazolo[1,5-a]azepine; Stable Isotope Labeled Tetrazoloazepine; Internal Standard 1329509-68-3
EINECS	Contact for details

Quality Control

Every batch of our deuterated compounds is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity as verified by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.