Description

(3S)-3-Deuterio-n-[Dideuterio-[(1S)-1,2,3,4-Tetrahydronaphthalen-1-Yl]Methyl]-1-Azabicyclo[2.2.2]Octan-3-Amine is a deuterated derivative of a complex amine, specifically designed for advanced research and development applications. This compound is critical for pharmaceutical and agrochemical discovery, where its deuterium-labeled structure provides unique metabolic stability and tracing capabilities. It is primarily utilized by research scientists and process chemists in the life sciences sector for drug metabolism and pharmacokinetics (DMPK) studies, mechanism of action research, and as a key intermediate in the synthesis of labeled active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research: As a deuterium-labeled internal standard for precise quantitative analysis in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• Drug Discovery & Development: For conducting metabolism studies, investigating pharmacokinetic profiles, and tracing metabolic pathways of lead compounds.
• Isotope Effect Studies: To evaluate the impact of deuterium substitution on the biological activity, stability, and toxicity of potential drug candidates.
• Synthetic Intermediate: Serves as a specialized building block for the synthesis of more complex, deuterated molecules in medicinal chemistry.
• Agrochemical Research: Used in the development and environmental fate studies of novel pesticides and herbicides.
• Academic Research: A valuable tool in universities and research institutes for fundamental studies in organic chemistry and biochemistry involving isotope labeling.

Basic Information

Product Name	(3S)-3-Deuterio-n-[Dideuterio-[(1S)-1,2,3,4-Tetrahydronaphthalen-1-Yl]Methyl]-1-Azabicyclo[2.2.2]Octan-3-Amine
CAS No.	1329499-39-9
Molecular Formula	C19H24D3N2
Molecular Weight	~286.45 g/mol
Synonyms	Deuterated Quinuclidine-Tetralin Amine; (S)-3-Deutero-N-((S)-1,2,3,4-Tetrahydronaphthalen-1-yl-d2-methyl)quinuclidin-3-amine; 3-Deutero-N-(Tetralin-1-yl-d2-methyl)quinuclidin-3-amine; Deuterated Tetralin-Quinuclidine Amine; 1329499-39-9; (3S)-3-2H-N-[(1S)-1,2,3,4-Tetrahydronaphthalen-1-yl-1,1-2H2-methyl]-1-azabicyclo[2.2.2]octan-3-amine
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure the highest isotopic and chemical purity for research applications. Each batch is characterized using advanced analytical techniques including NMR (1H, 13C, 2H), High-Resolution Mass Spectrometry (HRMS), and HPLC to confirm identity, isotopic enrichment, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C under an inert atmosphere such as argon or nitrogen. The compound is moisture-sensitive; ensure the storage environment is dry and desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.